PEMANFAATAN EKSTRAK DAUN SELEDRI (Apium Graveolens) SEBAGAI ANTIKOAGULAN PENGGANTI EDTA (Ethylene Diamine Tetraacetic Acid) PADA PEMERIKSAAN JUMLAH TROMBOSIT
DOI:
https://doi.org/10.33651/jpkik.v6i2.146Keywords:
Celery Leaves, Platelets, EDTA (Ethylene Diamine Tetraacetic Acid)Abstract
Celery (Apium Graveolens) has the same content as EDTA, namely flavonoids which can be used as anticoagulants, these flavonoids play a role in inhibiting the platelet aggregation process so that researchers want to do a research about of celery leaf extract (Apium Graveolens) as a substitute for EDTA (Ethylene Diamine Tetraacetic Acid) anticoagulants. Acid) on the examination of the platelet count. This research method is a laboratory experiment, namely the manufacture of celery leaf extract (Apium Graveolens) and homogenized with blood, which is then examined the number of platelets with 4 treatments. The examination of the platelet count also used the anticoagulant EDTA as a comparison. The results of examining the number of platelets using celery leaf extract with a concentration of 50% and using EDTA anticoagulants have the same results, so it can be stated that celery leaf extract can be used as an alternative anticoagulant as a substitute for EDTA (Ethylene Diamine Tetraacetic Acid) anticoagulant.
References
Assinger, A. (2014). Platelets and infection - An emerging role of platelets in viral infection. Immunology, 10–12.
Fitrah, H. Al, Sukeksi, A., & Ariyadi, T. (2019). Perbedaan Hasil Pemeriksaan Jumlah Trombosit Menggunakan Antikoagulan EDTA dan Antikoagulan Ekstrak Batang Mangrove (Aegiceras Cornitulatum). Http://Repository.Unimus.Ac.Id, 1–2.
Hayward, C. P. M., Moffat, K. A., Raby, A., Israels, S., Plumhoff, E., Flynn, G., & Zehnder, J. L. (2010). Development of North American consensus guidelines for medical laboratories that perform and interpret platelet function testing using light transmission aggregometry. American Journal of Clinical Pathology, 134(6), 955–963. https://doi.org/10.1309/AJCP9V3RRVNZMKDS
Kemenkes, R. I. (2011). Pedoman Interpretasi Data Klinis. 1–83. http://farmalkes.kemkes.go.id/?wpdmact=process&did=MTcyLmhvdGxpbms=)
Pratini, N. P. W. A. P., Jiwantoro, Y. A., & Khusuma, A. (2019). Perbedaan Kadar Kolesterol Total Menggunakan Antikoagulan EDTA (CH 2 CO 2 H), Natrium Sitrat (Na 3 C 6 H 5 O 7 ), dan Natrium Oksalat (Na 2 C 2 O4). Jurnal Analis Medika Bio Sains (JAMBS), 6(2), 130–134. https://doi.org/10.32807/jambs.v6i2.146
Saputra, O., & Fitria, T. (2016). Khasiat Daun Seledri ( Apium graveolens ) Terhadap Tekanan Darah Tinggi Pada Pasien Hiperkolestrolemia. Majority, 5(2), 120–125.
Siswanto. (2017). Darah dan Cairan Tubuh. Diktat Fisiologi Veteriner I, 1–49.
Tyagi, S., J., Chirag, P., Dhruv, M., Ishita, M., Gupta, A. K., Usman, M. R. M., & Maheshwari, R. K. (2013). Medical Benefits of Apium Graveolens (Celery Herb). Journal of Drug Discovery and Therapeutics, 1(5), 36–38.
Published
How to Cite
Issue
Section
JPKIK : Jurnal Peneliian dan Kajian Ilmiah kesehatan is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License
You are free to :
Share — copy and redistribute the material in any medium or format
Adapt — remix, transform, and build upon the material for any purpose, even commercially
Under the following terms :
Attribution — You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
ShareAlike — If you remix, transform, or build upon the material, you must distribute your contributions under the same license as the original
No additional restrictions — You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits
