Testing the Effectiveness of Ethanol Extract of Horse Whip Leaves (Stachytarpheta Jamaicensis L.) towards Wounds in Mice (Mus musculus)
DOI:
https://doi.org/10.33651/jpkik.v9i1.520Keywords:
Horse Whip Leaves; Stachytarpheta jamaicensis; Mice Cut Wounds; Mus musculusAbstract
The horse whip leaves plant (Stachytarpheta jamaincensis) is an annual herbaceous shrub. Cuts are wounds that occur due to cuts by instruments or sharps objects. This study aims to determine the effectiveness of the ethanol extract of horse whip leaves on the healing of cuts in mice (Mus musculus) and the most effective concentration for healing cuts in mice. Design This study uses laboratory experimental methods. The sample used for each experimental group was 5 mice with a total of 5 groups, so this study used 25 mice with 3 treatments, namely the treatment (positive control (+), negative control (-), 25%, 50%, 75%). All data is tabulated and statistically analyzed with ANOVA. The conclusion shows that the concentration of horsetail leaf extract at a concentration of 75% is the most effective in healing cuts in mice when compared to horsetail leaf extract at concentrations of 50% and 25% in terms of the average percentage of healing from day 1 to day 7.
References
Arisanty IP. Panduan Praktis Pemilihan Balutan Luka Kronik Edisi 2. Jakarta: Mitra Wacana Medika; 2013.
Arisanty IP. Konsep Dasar Manajemen Perawatan Luka. EGC; 2014.
Maghfuri A. Keterampilan Dasar Perawatan Luka Bagi Pemula. Trans Info Media; 2015.
Kurniawaty E, Farmitalia CG, Rahmanisa S, Andriani S. Perbandingan Tingkat Kesembuhan Luka Sayat Terbuka antara Pemberian Etakridin Laktat dan Pemberian Propolis Secara Topikal Pada Tikus Putih (Rattus novergicus). Seminar Nasional Pakar Ke 1. 2018; 1:339–345.
Wahyudi. Formulasi Permen Pereda Radang Tenggorokan dari Daun Pecut Kuda (Stacytarpheta Jamaicensis) sebagai Pangan Fungsional. Jurnal Pangan dan Agroindustri. 2019; 7(4):31-41.
Kumala S, Bekti NDP, Aktivitas Antibakteri dan Antioksidan Daun Pecut Kuda ( Stachytarpheta jamaicensis L .) Secara Invitro. Jurnal Farmasi Indonesia. 2016;8(2):137-143.
Sulaiman MR, Zakaria ZA, Chiong HS, Lai SK, Israf DA, Azam Shah TM. Antinociceptive and Anti-Inflammatory Effects of Stachytarpheta jamaicensis (L.) Vahl (Verbenaceae) in Experimental Animal Models. Jurnal Medical Principles Practice. 2009;18(4):272-279.
Utami K, Sari I, Nurhafidhah, Pengaruh Pemberian Topikal Ekstrak Etanol Daun Pecut Kuda (Stachytarpheta Jamaicensis (L.) Vahl) Terhadap Penyembuhan Luka Terbuka Pada Punggung Mencit (Mus Musculus). Jurnal Pendidikan Kimia dan Ilmu Kimia. 2019:21-27.
Indrayani L, Soetjipto H, Sihasale L. Skrining Fitokimia dan Uji Toksisitas Ekstrak Daun Pecut Kuda (Stachytarpheta jamaicensis L. Vahl) terhadap Larva Undang Artemia salina Leach. Salatiga: Fakultas Sains dan Matematika, Universitas Kristen Satya Wacana; 2006.
Soni H, Singhai AK. A Recent Update of Botanicals for Wound Healing Activity. International Research Journal of Pharmacy. 2012.
Arikunto. Presudur penelitian suatu pendekatan peraktek. Jakarta: PT. Rikena Cipta; 2006.
Robins. Perilaku Organisasi. Jakarta: Salemba Empat; 2009.
Berman A. 2009. Buku Ajar Praktik Keperawatan Klinis, Kozier ? Erb. Alih Bahasa Meiliya et al. ECG. Jakarta.
Kaplan, NE, Hentz VR. Eemergency Management of Skin An Soft Tissue Wounds, An IIIustrated Guide. Little Brown, Boston USA; 2006.
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