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Abstract

Resistensi is not inhibition of bacterial growth by administration of sistemic antibiotics with normal doses of supposed or minimal inhibitory content. Staphylococcus  aureus is a circular gram-positive bacteria 0,7-1,2µm in diameter, arranged in irregular clusters such as grapes, anaerobic facultative, spore-free, and immobile. Diabetes melitus is a cronic disease caused by high blood sugar levels accompanied by metabolic abnormalities. Ulcer DM is an open wound in the skin layer into the dermis, which usually occurs on the soles of the feet. Antibiotics are substances produced by a microbe, aspecially fungi, which can inhibit or eredicate other types of microbes. The purpose of this study was to detemine whether the staphylococcus aureus bakteria were resistant to some antibiotics to be tested. This research method is explorative descriptive. The sample taken in this study was staphylococcus aureus bacteria isolated from diabetic food wound ulcers grown on Nutrient Agar (NA) and Muller Hington Agar (MHA) media. Observasions were made after the bacteria were incubated at a temperatur of 30° C for 24 hours. From the result of the test, the average inhibition zone formed in each antibiotic, namely ceftriaxcon antibiotics, is 21 mm (sensitive), ciprofloxacin  is 18 mm (sensitive), chloramfenicol is 17 mm (sensitive), sulbactam ampicilin  is 4,3 mm (resistant), and amoxicillin is 2,6 mm (resistant).

Keywords

Resistensi, Staphylococcus aureus, Diabetes melitus, Ulcer DM, Antibiotics

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